| |
|
|
Pearl
Tsang
Associate Professor,
Chemistry
PhD, University of Pennsylvania
BA, Barnard College
Address:
804 Crosley
P.O. Box 210172
Cincinnati, OH 45221-0172
phone:
513-556-2301
fax: 513-556-9293
pearl.tsang@uc.edu
http://www.che.uc.edu/faculty_staff/tsang_pearl.html
|
Biography:
Pearl Tsang obtained a BA from Barnard College, followed by a PhD at the University of Pennsylvania. After her postdoctoral positions in biological NMR, Dr. Tsang joined the faculty in the Department of Chemistry at UC. Professor Tsang is one of the several biochemists in this Department and as such her general research interests entail elucidation of structure-function relationships of proteins, nucleic acids and biomolecular complexes. One particular class of proteins studied in the Tsang lab corresponds to the aminoacyl tRNA (transfer RNA) synthetaseses. These are enzymes which are crucial for correct covalent linkage of a given amino acid to its corresponding tRNA molecule; this process is also known as 'charging' of the tRNA and is essential for accurate protein translation. These investigations are conducted in order to enhance our understanding of how these proteins carry out their function since their structural and dynamic properties are relevant to their functions. The research conducted in this lab typically involves the production, purification and characterization of the proteins and peptides studied and this involves use of molecular biology and protein purification techniques. The characterization of these molecules involves biophysical and spectroscopic (primarily solution NMR) techniques.
Research Areas:
• Biophysical studies of proteins and nucleic acids
• Biomolecular complexes
• Biomolecular solution NMR
|
<back>
|
|
|
