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Albert
M. Bobst
Professor,
Chemistry
PhD, University of Zuerich Switzerland, 1965
Address:
903 Crosley
PO Box 210172
Cincinnati, OH 45221
phone:
513-556-9281
fax: 513-556-9239
albert.bobst@uc.edu
http://www.che.uc.edu/faculty_staff/Bobst_Albert.html
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Biography:
Albert Bobst is Professor of Chemistry and Biological Chemistry at the University of Cincinnati. After receiving his PhD at the University of Zurich in 1965, where he characterized Tetrahydropterins by nuclear magnetic resonance, he spent a postdoctoral year in Paris at the Institut de Biologie Physico-Chimique with Professor Pullman studying Quantum Biochemistry. Subsequently he was awarded a Swiss National Science Fellowship to study under the guidance of Professor Calvin and Tinoco Photosynthesis and Nucleic Acid Chemistry at Berkeley, California. In 1968 he went to Princeton University as a Research Associate before joining the faculty at the University of Cincinnati in 1969. He was a visiting scientist at the National Institutes of Health in 1976 and 1984, and also at the ISREC in Lausanne, Switzerland in 1979.
Research Areas:
A) Application of electron paramagnetic resonance (EPR) spectroscopy: 1) to study dynamic features of nucleic acids and nucleic acid – protein complexes, and 2) to detect free radical damage in biological systems.
B) Synthesis of spin-labeled nucleic acids as hybridization probes for genome detection by EPR.
C) Development of kits for detecting the presence or absence of genes with a table top EPR instrument.
D) Molecular modeling of nucleic acids and nucleic acid – protein complexes.
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